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fsrA [2019-07-12 12:46:22]
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fsrA [2019-07-12 12:46:22]

regulatory RNA
essential
no
synonyms
Outlinks
KEGGBsubCyc

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.5|Regulatory RNAs]

    • Gene

    Phenotypes of a mutant

  • transcription profile of a [gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA] mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] [pubmed|22389480]

    • RNA

    basic information/Evolution

  • Catalyzed reaction/ biological activity: hybridizes to [gene|81429F7802CD4B1F7DFDB6C900D7DA5ECA6B9F3F|sdhC], [gene|E15E9F88B0E03FE8834C646369D2F4B4E713EF41|citB], [gene|57B9E37F6232189CD47C1B41FDCF43FCB8016AEB|lutB], [gene|44DF1B7E476AD58B3CCC39300FFE0132D0D32AD0|gltA]-[gene|AA07CC52B2DD48ACC9D3375E9D531CB1ACBE485A|gltB], and [gene|AC459429A9C50463FD947C1CF9EA919B6FE3B335|leuC]-[gene|0EB4C6EE398B14B9284FFAEDBC26C866CE2070D7|leuD] mRNAs and inhibits their translation [pubmed|18697947,22389480]

    • Expression and Regulation

    Operons

    genes
    [gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]: repression, [pubmed|18697947], in [regulon|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur regulon]

    • regulation

  • induced by iron starvation (third wave, under extreme starvation, iron sparing response) ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]) [pubmed|29133393,18697947]
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    Biological materials

    Mutant

  • HB7361 Δ[gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]::''cat'' (available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs) [pubmed|18697947]
  • HB7385 Δ[gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]::''spc'' (available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs) [pubmed|18697947]

    • labs

  • [SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]

    • References

  • 22427629,18697947,22389480,29133393